IACUC Process

Pre-Review Stage

The PI or a designated member of the study team must complete a submission form (for Initial or Triennial (De Novo) Protocol Review, Protocol Continuation, Protocol Modification/Amendment, Protocol Reporting, or Protocol Closeout) in the iRIS electronic compliance platform. The form must be reviewed and approved by the IACUC before the requested protocol activity can commence. The linked document provides a visual of this process. 

ORRC Preview Stage

The ORRC receives the submission and reviews it for completeness and initial adherence to federal, state, and local regulations. If any information is missing from the submission, the PI and any authorized study personnel will be notified and asked to make corrections. If the submission is complete, it will be assigned to a review process and to an IACUC member(s) for review. If the submission requires review by the full Committee, the ORRC schedules the submission for review at the next available IACUC meeting as indicated by the IACUC submission and deadline schedule. 

IACUC Review Stage

The submission is reviewed by at least one IACUC member or in some cases, by a member of the ORRC. This review process can take up to 6 weeks depending on the type of review, complexity of the study,

• Exempt Reviews can take up to 2 weeks
• DMR Reviews can take up to 4 weeks
• Full Board reviews can take up to 6 weeks

Post-Review Stage

Once the regulatory compliance review is complete, an outcome letter will be sent to the study PI and authorized study personnel indicating that the submission was approved/accepted, disapproved/unaccepted, requires revisions, may be approved pending the administrative review of given conditions, or the review has been tabled for a given reason. Depending on the outcome, further information may be requested prior to the full approval of the submission.